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To determine the influence of phacoemulsification on choroidal vasculature in patients with diabetic retinopathy (DR) undergoing cataract surgery
To determine the influence of phacoemulsification on choroidal vasculature in patients with diabetic retinopathy (DR) undergoing cataract surgery through the follow-up of choroidal thickness (CT) and choroidal vascularity index (CVI) using swept-source optical coherence tomography (SS-OCT) system.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| control | the age-related cataract patients | ||
| DR group | the cataract patients with mild/moderate NPDR |
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| Measure | Description | Time Frame |
|---|---|---|
| CVI at baseline | choroidal vascularity index(CVI) was defined as the proportion of vascular area to total circumscribed area. | CVI was assessed at baseline(within 1 week before surgery) |
| CVI at 1 week postoperatively | choroidal vascularity index (CVI) was defined as the proportion of vascular area to total circumscribed area. | CVI was assessed 1 week after surgery. |
| CVI at 1 month postoperatively | choroidal vascularity index (CVI) was defined as the proportion of vascular area to total circumscribed area. | CVI was assessed 1 month after surgery. |
| CVI at 3 months postoperatively | choroidal vascularity index (CVI)was defined as the proportion of vascular area to total circumscribed area. | CVI was assessed 3 months after surgery. |
| CT at baseline | Choroid thickness (CT) was the thickness of the choroidal layer; CT values were obtained with the built-in software of the SS-OCT device. | CT was assessed at baseline and 1 week, 1 month, 3 month after surgery. |
| CT at 1 week postoperatively | Choroid thickness (CT) was the thickness of the choroidal layer; CT values were obtained with the built-in software of the SS-OCT device. | CT was assessed at 1 week after surgery. |
| CT at 1 month postoperatively |
| Measure | Description | Time Frame |
|---|---|---|
| IOP at baseline | IOP was the value of intraocular pressure. | IOP was assessed at baseline and 1 week, 1 month, 3 month after surgery. |
| IOP at 1 week postoperatively | IOP was the value of intraocular pressure . |
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Inclusion Criteria:
Exclusion Criteria:
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23 eyes of 23 cataract patients with mild/moderate NPDR without DME, and 23 age-matched non-diabetic patients
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| Name | Affiliation | Role |
|---|---|---|
| Xi Shen, PhD | Shanghai Jiao Tong University School of Medicine | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ruijin Hospital | Shanghai | Shanghai Municipality | 200025 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33178452 | Derived | Yao H, Gao S, Liu X, Zhou Y, Cheng Y, Shen X. Choroidal Structural Changes Assessed with Swept-Source Optical Coherence Tomography after Cataract Surgery in Eyes with Diabetic Retinopathy. J Ophthalmol. 2020 Oct 29;2020:5839837. doi: 10.1155/2020/5839837. eCollection 2020. |
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| ID | Term |
|---|---|
| D003930 | Diabetic Retinopathy |
| ID | Term |
|---|---|
| D012164 | Retinal Diseases |
| D005128 | Eye Diseases |
| D003925 | Diabetic Angiopathies |
| D014652 | Vascular Diseases |
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Choroid thickness (CT) was the thickness of the choroidal layer; CT values were obtained with the built-in software of the SS-OCT device.
| CT was assessed at 1 month after surgery. |
| CT at 3 months postoperatively | Choroid thickness (CT) was the thickness of the choroidal layer, CT values were obtained with the built-in software of the SS-OCT device. | CT was assessed at 3 months after surgery. |
| VD at baseline | VD of the choriocapillaris was the vessel density of the choriocapillaris in the choroid. | VD of the choriocapillaris was assessed at baseline. |
| VD at 1 week postoperatively | VD of the choriocapillaris was the vessel density of the choriocapillaris in the choroid. | VD of the choriocapillaris was assessed 1 week after surgery. |
| VD at 1 month postoperatively | VD of the choriocapillaris was the vessel density of the choriocapillaris in the choroid. | VD of the choriocapillaris was assessed 1 month after surgery. |
| VD at 3 months postoperatively | VD of the choriocapillaris was the vessel density of the choriocapillaris in the choroid | VD of the choriocapillaris was assessed 3 months after surgery. |
| IOP was assessed 1 week after surgery. |
| IOP at 1 month postoperatively | IOP was the value of intraocular pressure. | IOP was assessed 1 month after surgery. |
| IOP at 3 months postoperatively | IOP was the value of intraocular pressure . | IOP was assessed 3 months after surgery. |
| BCVA at baseline | BCVA was the best corrected visual acuity. | BCVA was assessed at baseline . |
| BCVA at 3 months postoperatively | BCVA was the best corrected visual acuity. | BCVA was assessed 3 months after surgery. |
| D002318 |
| Cardiovascular Diseases |
| D048909 | Diabetes Complications |
| D003920 | Diabetes Mellitus |
| D004700 | Endocrine System Diseases |