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We evaluated the clinical effect of Butorphanol on postoperative analgesia by observing the vital signs of patients, general condition of newborns and pain assessment.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Observed group | Experimental |
| |
| Control group | No Intervention |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| butorphanol | Drug | Observed group:Intravenous drip of Butorphanol in patients after cesarean section;control group: intravenous drip of saline in patients after cesarean section |
|
| Measure | Description | Time Frame |
|---|---|---|
| change from Visual Analogue Score for pain | VAS is the most common pain scale for quantification. The score is higher, the patient will be more painful. That will indicate if the analgesia is effective. Visual analog scale (VAS) ranging from 0 to 10 (with 10 representing the worst pain imaginable) to measure the degree of pain for participants | assess VAS at 24 hours, 25 hours, 26 hours, 27 hours, 30 hours, 36 hours after the cesarean section |
| Measure | Description | Time Frame |
|---|---|---|
| heart rates | heart rates（bpm) | at 24 hours, 30 hours, 36 hours after the cesarean section |
| jaundice index of the newborn,1 minute and 5 minutes Apgar score | Neonatal Apgar scores at the first and fifth minute.The score indicates the infant s' conditions, including heart rate, breathing, muscle tone, reflex response, color. Each characteristic is given an individual score; two points for each of the five categories if all is completely well; then all scores are totaled. The score is from 0 to 10. |
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Inclusion Criteria:
Healthy women at term (37 to 42 weeks of gestation), who desired cesarean section were eligible to participate. undergoing ï¼›No drug sensitive history
Exclusion Criteria:
Patients with a history of anesthetics allergy and patients with preterm labor, multiple pregnancies and severe obstetric complications
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Xun Gong, Doctor | Contact | 13886174675 | gongxun4019@163.com |
| Name | Affiliation | Role |
|---|---|---|
| Xun Gong | Tongji Hospital | Study Chair |
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| ID | Term |
|---|---|
| D000377 | Agnosia |
| ID | Term |
|---|---|
| D010468 | Perceptual Disorders |
| D019954 | Neurobehavioral Manifestations |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
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| ID | Term |
|---|---|
| D002077 | Butorphanol |
| ID | Term |
|---|---|
| D009019 | Morphinans |
| D053610 | Opiate Alkaloids |
| D000470 | Alkaloids |
| D006571 | Heterocyclic Compounds |
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| jaundice index: 24 hours, 48 hours, 72 hours after the cesarean section |
| blood pressure | blood pressure(mmHg) | at 24 hours, 30 hours, 36 hours after the cesarean section |
| breath | breath(bpm) | at 24 hours, 30 hours, 36 hours after the cesarean section |
| pulse | pulse(bpm) | at 24 hours, 30 hours, 36 hours after the cesarean section |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D006572 |
| Heterocyclic Compounds, Bridged-Ring |
| D006576 | Heterocyclic Compounds, 4 or More Rings |
| D000072471 | Heterocyclic Compounds, Fused-Ring |
| D010616 | Phenanthrenes |
| D011084 | Polycyclic Aromatic Hydrocarbons |
| D011083 | Polycyclic Compounds |