Periodontal Management in Hypertensive Patients (PERIOTENSION Trial I)

Periodontal Management in Hypertensive Patients

Treated hypertensive patients with any form of periodontal diseases will be randomized to either supragingival dental plaque removal using electric toothbrushes at home or intensive professional oral hygiene treatment and the effects on blood pressure will be identified.

Inclusion Criteria:

• Treated hypertension
• Have at least 20 natural teeth
• Presence of any form of periodontal diseases according to guidelines
• Absence of other significant oral infections.

Exclusion Criteria:

• Secondary hypertension (known plasma renin screening, abdominal ultrasound with doppler and other investigations)
• Individual is pregnant or nursing
• Primary pulmonary hypertension
• Professional oral hygine within past 6 months
• Flu, rhinitis, sinusitis etc. within past 4 weeks
• Use of antibiotics within past 4 weeks
• Hospitalization for any reason within the past 3 months
• Allergic disorders; History of chronic infectious disease,
• Chronic hepatitis B or C infection
• Chronic Obstructive Pulmonary Disease (COPD), tuberculosis
• Other known chronic inflammatory or autoimmune condition such as lupus or rheumatoid arthritis, ulcerative colitis or Crohn's disease
• Use of systemic or local steroids or immunosuppressive agents within 6 months of the inclusion.
• History of alcohol abuse or unwillingness to limit alcohol consumption to less than 4 drinks per week