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As part of a prospective study, to evaluate the effect of periodontitis on the course of hypertension at baseline, during 6 and 12 months
The study focuses on following tasks: to evaluate and compare arterial stiffness in patients with hypertension and the control group, the effect of treatment and control of clinical manifestations of periodontitis in patients with hypertension and the control group, the effect of treatment and control of clinical manifestations of periodontitis on the level of CRP in patients with hypertension and the control group, the effect of periodontitis control on the dynamics of OH, LDL, TG, uric acid, and fasting glycemia levels, the effect of periodontitis on the risk of atrial fibrillation/flutter in patients with arterial hypertension, to develop an information platform for patients with periodontitis for early detection of CVD risks and control of modifiable risk factors
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Periodontitis group |
| ||
| Control group |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Orthopantomography | Diagnostic Test | Orthopantomography |
|
| Measure | Description | Time Frame |
|---|---|---|
| Triglyceride level | Triglyceride level | 12 months from inclusion |
| Low density lipoprotein level | Low density lipoprotein level | 12 months from inclusion |
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Inclusion Criteria:
Exclusion Criteria:
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The study is set to include 200 patients (both sexes) over 18 years of age with arterial hypertension who signed the informed consent form for participation in the study: 100 patients with periodontitis and 100 patients without periodontitis - control group
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| Name | Affiliation | Role |
|---|---|---|
| Olga Trushina, MD, PhD | Sechenov University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University hospital #1 | Moscow | Russia |
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| ID | Term |
|---|---|
| D006973 | Hypertension |
| D010518 | Periodontitis |
| D007249 | Inflammation |
| ID | Term |
|---|---|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D010510 | Periodontal Diseases |
| D009059 | Mouth Diseases |
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| ID | Term |
|---|---|
| D011862 | Radiography, Panoramic |
| ID | Term |
|---|---|
| D011861 | Radiography, Dental |
| D011859 | Radiography |
| D003952 | Diagnostic Imaging |
| D019937 | Diagnostic Techniques and Procedures |
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| D009057 |
| Stomatognathic Diseases |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D003933 | Diagnosis |
| D003945 | Diagnosis, Oral |
| D003813 | Dentistry |