Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Adenoviral Sub epithelial infiltrates (SEI) affect ocular function.They lead to reduced vision, photophobia, glare, halos, and foreign body sensation.
first group of patients were treated with 0.03 % tacrolimus ointment twice daily for 6 months.S econd group underwent transepithelial PTK for subepithelial infiltrates. Baseline and post-treatment full ophthalmic examination was done.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Tacrolimus | Patients were treated with 0.03 % tacrolimus ointment twice daily for 6 months. |
| |
| Phototherapeutic Keratectomy | Patients underwent transepithelial PTK for subepithelial infiltrates. |
| |
| Control | patients received only artificial tears eyedrop |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Tacrolimus ointment | Drug | Patients were treated with 0.03 % tacrolimus ointment twice daily for 6 months. |
|
| Measure | Description | Time Frame |
|---|---|---|
| changes of corneal densitometry | Sub epithelial infiltrates was examined with the densitometry programme of the Pentacam (Fa. Oculus,Weimar, Germany) | 6 months |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
60 patients with adenoviral SEI
Not provided
| Name | Affiliation | Role |
|---|---|---|
| TAREK R ELHAMAKY | Benha university faculty of medicine | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| INMC | Abu Dhabi | 46266 | United Arab Emirates |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 32852646 | Derived | Elhamaky TR. Pentacam corneal densitometry-guided treatment of adenoviral corneal subepithelial infiltrates: a comparative study between transepithelial phototherapeutic keratectomy and topical tacrolimus. Int Ophthalmol. 2021 Jan;41(1):67-77. doi: 10.1007/s10792-020-01553-8. Epub 2020 Aug 27. |
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D003316 | Corneal Diseases |
| D000257 | Adenoviridae Infections |
| ID | Term |
|---|---|
| D005128 | Eye Diseases |
| D004266 | DNA Virus Infections |
| D014777 | Virus Diseases |
| D007239 | Infections |
Not provided
Not provided
Not provided
Not provided
Not provided
| phototherapeutic keratectomy | Procedure | Patients underwent transepithelial PTK for subepithelial infiltrates. |
|