Contact Lenses and Infiltrative Keratitis

Contact Lenses and Infiltrative Keratitis

To quantify and compare baseline tear proteins and ocular response in contact lens wearers with a history of corneal infiltrative events, to those without a history of complications. This will be accomplished via measurement of select anti-inflammatory tear proteins before, during and after contact lens wear.

Inclusion Criteria:

• Soft contact lens wearers
• Healthy (control), or with history of infiltrative keratitis (case)
• Has a wearable pair of glasses
• Refractive error between +8.00 D and -12.00 D, with less than 1.50 D of astigmatism

Exclusion Criteria:

• Smoker
• Pregnant or nursing
• Systemic disease that would effect tear proteins
• Punctal plugs
• Use of eye drops in the last week