Serum Ferritin and Hepicidin Concentration in Chronic Periodontitis Patients With T2DM

Decreased Ferritin And Increased Hepcidin Serum Levels In Periodontitis Patients With Diabetes Mellitus Type 2. Controlled Before-And-After Study

serum level of ferritin and hepicidin were evaluated in periodontitis patient with and without type 2 diabetes before and after non surgical periodontal treatment to clarify their in periodontal disease

Inclusion Criteria:

• patients with more than 30% of the sites had clinical attachment level (CAL) 3-4mm with T2DM
• systemically healthy patients with more than 30% of the sites had clinical attachment level (CAL) 3-4mm
• healthy subjects had clinically healthy gingiva with ≤ 3mm pocket probing depth (PPD), nearly zero plaque index (PI), gingival index (GI), zero CAL.

Exclusion Criteria:

• (I) Pregnancy or lactation, (II) History of receiving professional periodontal treatment during the past 6 months; (III) Treatment with any type of medications and/ or antibiotics during the past 3 months and (IV) Current or former smokers.