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Researchers are trying to identify is chewing gum improves bowel function after anterior lumbar interbody fusion
Aims, purpose, or objectives:
Background (Include relevant experience, gaps in current knowledge, preliminary data, etc.):
One or two level anterior lumbar interbody fusions are designed to correct lumbar spondylosis and spondylolisthesis, which can cause debilitating back and leg pain. This surgery involves an anterior approach, which often requires displacement of bowel for the length of the surgery. Patients frequently have a slow return of bowel function secondary to anesthetic time, opioid use, and primarily due to the bowel displacement intraoperatively. Because this is a one or two level surgery, many patients would benefit from same-day discharge but often remain inpatient several days due to slow return of bowel function.
Gum chewing has been shown to decrease the time for return to bowel function (RBF) in colorectal and gynecology patients postoperatively.
Gum chewing and RBF has been studied in the spine population for posterior operations but not anterior spine surgery. This study aims to identify whether chewing gum has an impact on patient's report of pain, RBF, length of stay, and subjective report of satisfaction post-operatively. This could be an outpatient operation; however, pain and RBF often prevent patients from discharging home the same day of surgery.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Gum chewing | Experimental | Chew xylitol based, peppermint flavored gum for 30 minutes every two hours during the hours of 7 am to 9 pm, for the first 24 hours after your surgery |
|
| Standard Care | No Intervention | Standard hospital management with no deviations from usual care |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Chewing gum | Other | xylitol based, peppermint flavored gum |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in bowel pattern based on gum-chewing | Number of hours until return of bowel sounds | 24 hours after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Bowel function | Number of hours until return of flatus | Number of hours from admission to discharge up to 48 hours |
| Length of time to return of bowel function after anterior lumbar interbody fusion |
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Inclusion Criteria:
Exclusion Criteria:
Some participants may subsequently undergo a posterior spinal fusion on the same-day of surgery. They will not be excluded, but the investigators will include this group in a different data subset.
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| Name | Affiliation | Role |
|---|---|---|
| Maziyar Kalani, MD | Mayo Clinic | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Mayo Clinic Hospital | Phoenix | Arizona | 85054 | United States |
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| Label | URL |
|---|---|
| Mayo Clinic Clinical Trials | View source |
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| ID | Term |
|---|---|
| D055009 | Spondylosis |
| D013168 | Spondylolisthesis |
| ID | Term |
|---|---|
| D013122 | Spinal Diseases |
| D001847 | Bone Diseases |
| D009140 | Musculoskeletal Diseases |
| D013169 | Spondylolysis |
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| ID | Term |
|---|---|
| D002638 | Chewing Gum |
| ID | Term |
|---|---|
| D053149 | Plant Gums |
| D001704 | Biopolymers |
| D011108 | Polymers |
| D046911 | Macromolecular Substances |
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Number of hours until complete bowel movement
| Number of hours from admission to discharge up to 48 hours |
| Total length of hospital | Number of hours of hospital stay | Number of hours from admission to discharge up to 48 hours |
| Pain score | On a scale of 0 (zero pain) and 10 (worst pain) | 24 hours post-operatively |
| D011134 |
| Polysaccharides |
| D002241 | Carbohydrates |
| D053147 | Plant Exudates |
| D001688 | Biological Products |
| D045424 | Complex Mixtures |
| D002182 | Candy |
| D005502 | Food |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
| D019602 | Food and Beverages |