Not provided
Not provided
Not provided
Not provided
Covid-19 restrictions
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| Standard Process Inc. | INDUSTRY |
Not provided
Not provided
Not provided
Not provided
To quantify the glycemic index of the SP energy-smart-based nutrition supplement and the SP Glucose-support formula as compared to a glucose drink. We hypothesized that both the energy-smart-based nutritional supplement and the SP Glucose-support formula will have low glycemic index.
The aim of the study is to quantify the glycemic index of the SP energy-smart-based nutrition supplement and the SP Glucose-support formula as compared to a glucose drink. We hypothesized that both the energy-smart-based nutritional supplement and the SP Glucose-support formula will have low glycemic index.
Subjects: 9 non-diabetic (HbA1c < 6.5) males aged 30-55 years with body mass indices ranging from 27.5 to 35 kg∙m-2. Individuals with impaired glucose tolerance will be included as long as they are not diagnosed with diabetes and their HbA1c is less than 6.5.
Preliminary Testing: Medical history, weight, height, body composition via dual x-ray absorptiometry (DXA) and glycosylated hemoglobin (HbA1c) measurement.
Protocol: After a 10-hour overnight fast, subjects will complete 3 experimental visits in which they will ingest one of three beverages in a randomized order. During experimental visits subjects will either be given the following 3 experimental drinks:
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Standard Process - glucose balance | Experimental | Standard Process - glucose balance formula (200 kcal) |
|
| Energy smart Carbohydrate blend | Experimental | Energy smart carbohydrate blend (50 grams, 200 kcal) |
|
| Liquid Dextrose Control | Active Comparator | Liquid dextrose solution in the form of TRUTOL ® Glucose Tolerance Test Beverage (50 grams, 200 kcal) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Carbohydrate drink | Dietary Supplement | Meal replacement drink containing 200 kcal |
|
| Measure | Description | Time Frame |
|---|---|---|
| Area Under the Curve of Glucose | Positive integer of the area under the Curve of glucose | 120 minutes |
| Area Under the Curve for Insulin | Positive integer of the area under the Curve of insulin | 120 minutes |
| Blood glucose | Blood glucose levels | 30, 60 and 120 minutes of the glucose challenge |
| Blood insulin | Blood insulin levels | 30, 60 and 120 minutes of the glucose challenge |
| Measure | Description | Time Frame |
|---|---|---|
| c-peptide | Blood levels of c-peptide | 30, 60, and 120 minutes of the glucose challenge |
| glucagon | Blood levels of glucagon | 30, 60, and 120 minutes of of the glucose challenge |
Not provided
Inclusion Criteria:
Exclusion Criteria:
self-reported
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Stavros Kavouras, PhD | Arizona State University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Arizona Biomedical Collaborative | Phoenix | Arizona | 85004 | United States |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Randomized Cross-over trial
Not provided
Not provided
Not provided
| Energy smart Carbohydrate blend | Dietary Supplement | Carbohydrate blend drink designed for low glycemic responses containing 200 kcal |
|
| Liquid Dextrose | Dietary Supplement | Liquid Dextrose drink of 200 kcal |
|
| Leptin | Blood levels of leptin | 30, 60, and 120 minutes of the glucose challenge |
| Adiponectin | Blood levels of adiponectin | 30, 60, and 120 minutes of the glucose challenge |
| glucagon-like-peptide-1 | Blood levels of glucagon-like-peptide-1 | 30, 60, and 120 minutes of the glucose challenge |