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Study clinical characteristics and phenotypes of patients diagnosed with NSAID sensitivity in Thailand
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| NSAID sensitivity | Patients diagnosed with an immediate reaction to aspirin/NSAIDs/or paracetamol |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| aspirin, NSAIDs, paracetamol | Drug | Perform skin test and/or provocation test with aspirin, paracetmol, or suspected NSAIDs in questionable cases |
|
| Measure | Description | Time Frame |
|---|---|---|
| Results of skin test/provocation test | Positive, negative, or equivocal | 4 years |
| Measure | Description | Time Frame |
|---|---|---|
| Phenotypes of allergic reactions | 4 years | |
| Urine leukotriene E4 | 4 years |
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Inclusion Criteria:
Exclusion Criteria:
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Patients at least 15 years of age with a history of an immediate reaction to aspirin/paracetamol, or NSAIDs
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| Name | Affiliation | Role |
|---|---|---|
| Jettanong Klaewsongkram, MD | Chulalongkorn University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Medicine, Chulalongkorn University | Bangkok | 10330 | Thailand |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33474858 | Result | Klaewsongkram J, Buranapraditkun S, Mongkolpathumrat P, Palapinyo S, Chantaphakul H. Clinical Characteristics, Urinary Leukotriene E4 Levels, and Aspirin Desensitization Results in Patients With NSAID-Induced Blended Reactions. Allergy Asthma Immunol Res. 2021 Mar;13(2):229-244. doi: 10.4168/aair.2021.13.2.229. |
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Sputum, urine
| ID | Term |
|---|---|
| D055963 | Asthma, Aspirin-Induced |
| ID | Term |
|---|---|
| D001249 | Asthma |
| D001982 | Bronchial Diseases |
| D012140 | Respiratory Tract Diseases |
| D012130 | Respiratory Hypersensitivity |
| D006969 | Hypersensitivity, Immediate |
| D006967 | Hypersensitivity |
| D007154 | Immune System Diseases |
| D004342 | Drug Hypersensitivity |
| D064420 | Drug-Related Side Effects and Adverse Reactions |
| D064419 | Chemically-Induced Disorders |
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| ID | Term |
|---|---|
| D001241 | Aspirin |
| D000894 | Anti-Inflammatory Agents, Non-Steroidal |
| D000082 | Acetaminophen |
| ID | Term |
|---|---|
| D012459 | Salicylates |
| D062385 | Hydroxybenzoates |
| D010636 | Phenols |
| D001555 | Benzene Derivatives |
| D006841 | Hydrocarbons, Aromatic |
| D006844 | Hydrocarbons, Cyclic |
| D006838 | Hydrocarbons |
| D009930 | Organic Chemicals |
| D018712 | Analgesics, Non-Narcotic |
| D000700 | Analgesics |
| D018689 | Sensory System Agents |
| D018373 | Peripheral Nervous System Agents |
| D045505 | Physiological Effects of Drugs |
| D020228 | Pharmacologic Actions |
| D020164 | Chemical Actions and Uses |
| D000893 | Anti-Inflammatory Agents |
| D045506 | Therapeutic Uses |
| D018501 | Antirheumatic Agents |
| D000083 | Acetanilides |
| D000813 | Anilides |
| D000577 | Amides |
| D000814 | Aniline Compounds |
| D000588 | Amines |
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