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Garlic extract as herbal compound has potent antibacterial properties and can be used safely as an irrigant for pulpectomy procedure of primary molars root canals with high clinical and radiographic outcomes
Aim: This study indented to assess the clinical and radiographic assessment of garlic extract as an intracanal irrigant for pulpectomy of primary molars.
Methodology: 91 child with 100 teeth submitted into this study were equally categorized into the test group (group 1) which irrigated with garlic extract and control group (group 2) that received sodium hypochlorite (NaOCl). Then, each group has been subjected to further specification according to the tooth preoperative clinical and radiographic features into has been into 2 subgroups. Clinical and radiographic success rates were checked at 3, 6 and 12 months. Fisher's exact test for binary variable was used for data analysis with p-value ⤠0.05.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Garlic extracts root canal irrigation group | Experimental | Experimental group treated with garlic extract A 100 gram of garlic cloves has been cleaned, peeled and dried. Ethanol of 70% concentration was added for 60 seconds. The cloves were placed in a laminar airflow chamber for evaporation of residual ethanol. Using a sterile mortar and pestle, cloves were homogenized aseptically and filtered through a double layer paper. The fully concentrated extracted was diluted to the concentration of 25% with distilled water |
|
| Sodium hypochlorite root canal irrigation group | Active Comparator | Control group which treated conventionally using .5 ml of 5.25% NaOCl (COLTENE®ENDO, Switzerland) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Garlic extract | Other | A 100 gram of garlic cloves has been cleaned, peeled and dried. Ethanol of 70% concentration was added for 60 seconds. The cloves were placed in a laminar airflow chamber for evaporation of residual ethanol. Using a sterile mortar and pestle, cloves were homogenized aseptically and filtered through a double layer paper. The fully concentrated extracted was diluted to the concentration of 25% with distilled water |
| Measure | Description | Time Frame |
|---|---|---|
| oral examination | Pain assessment using Visual Analog Score for pain | 12 months |
| radiographic success or failure | Radiographic assessment using periapical radiograph and score (0) applied for absence of radiolucency and score (1) for presence of radiolucency | 12 months |
| Measure | Description | Time Frame |
|---|---|---|
| Types of failures | detecting the percent of different failure types accompanied with pulpectomy procedures after using garlic as an irrigant solution. | 12 months |
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Inclusion Criteria:
1. Normal radiographic findings
2. Interruption of lamina dura
3. Furcation radiolucency
Exclusion Criteria:
Specifications of exclusion
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31452953 | Derived | Elheeny AAH. Allium sativum extract as an irrigant in pulpectomy of primary molars: A 12-month short-term evaluation. Clin Exp Dent Res. 2019 Jun 26;5(4):420-426. doi: 10.1002/cre2.197. eCollection 2019 Aug. |
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| Type | Date | Date Unknown |
|---|---|---|
| Release | Feb 11, 2020 | |
| Reset | Feb 26, 2020 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Feb 11, 2020 | Feb 26, 2020 |
| ID | Term |
|---|---|
| C000594566 | PMK-S005 |
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|
| NaOCl (COLTENEĀ®) | Other | Sodium hypochlorite |
|