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Allium Sativum oil is advocated to prove the capability of new natural products in replacing higher cost pharmacological materials, while achieving the same successful clinical and radiographic long-term results.
One of the most challenging subjects in paediatric dentistry is choosing the ideal pulp medication material that has the required properties such as preserving the vitality of the remaining intact pulp and stimulating its repair. This material should prevent pathological root resorption.Clinical and cost effectiveness trials from different countries are useful to determine which medicament should be advocated in which economic setting . Alternative pulpotomy materials clinically effective as MTA but with lower cost should be studied .
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Allium sativum oil | Experimental | The pulp stumps of the molars are dressed with a cotton pellet that is made damp with Allium Sativum oil for 1 min . |
|
| Mineral Trioxide Aggregate | Active Comparator | The material will be prepared according to the manufacturer's instructions , applied to the pulp chamber and a moistened cotton pellet was placed over the MTA paste to allow the material to set. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Allium Sativum Oil | Drug | Garlic oil Captain Company (CAP-PHARM) |
|
| Measure | Description | Time Frame |
|---|---|---|
| Clinical effectiveness | clinical effectiveness will be measured by intraoral examination and radiographic assessment | 1 year follow up |
| Measure | Description | Time Frame |
|---|---|---|
| Cost-effectiveness | cost-effectiveness will be measured with incremental cost-effectiveness ratio (ICER) | 1 year follow up |
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Inclusion Criteria:
Exclusion Criteria:
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It is a double-blinded randomised clinical trial with equal randomisation parallel design with allocation ratio 1:1
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participants and outcome assessor will be blinded (double blind study )
| Mineral Tri-Oxide Aggregate | Drug | ProRoot MTA, Dentsply |
|
|
| ID | Term |
|---|---|
| C038491 | allyl sulfide |
| C000632580 | TheraCal |
| D000068437 | Pemetrexed |
| ID | Term |
|---|---|
| D006147 | Guanine |
| D007042 | Hypoxanthines |
| D011688 | Purinones |
| D011687 | Purines |
| D006574 | Heterocyclic Compounds, 2-Ring |
| D000072471 | Heterocyclic Compounds, Fused-Ring |
| D006571 | Heterocyclic Compounds |
| D005971 | Glutamates |
| D024342 | Amino Acids, Acidic |
| D000596 | Amino Acids |
| D000602 | Amino Acids, Peptides, and Proteins |
| D000600 | Amino Acids, Dicarboxylic |
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