Immunological Tolerance After Frequent Rabies Booster Vaccinations

Immunological Tolerance After Frequent Rabies Booster Vaccinations

To study immunological tolerance effect after frequent rabies booster vaccination

Previous studies had shown lower antibody titers among those who received frequent rabies booster vaccination, compared to ones who had got primary immunization. We study immunological cells i.e., regulatory T cell, regulatory B cell, T follicular helper cell, and cytokines in those who received frequent rabies booster vaccination.

Inclusion Criteria:

• Healthy adults
• Previously received rabies vaccination

Exclusion Criteria:

• Had immunocompromised conditions
• Received blood or blood product within 3 months
• Received anti-malarial drugs