Efficacy and Safety of Chuna Manual Treatment as an Adjunctive Therapy After Total Knee Arthroplasty: A Study Protocol for a Single-Center, Randomized, Assessor Blind, Parallel-Group Clinical Trial

Efficacy and Safety of Chuna Manual Treatment as an Adjunctive Therapy After Total Knee Arthroplasty: A Study Protocol for a Single-Center, Randomized, Assessor Blind, Parallel-Group Clinical Trial

Evaluate the efficacy and safety of Chuna treatment as an adjunctive therapy in patients with moderate pain following total knee replacement.

Inclusion Criteria:

• Patients with NRS of knee pain ≥4 during the 7 days after 3 months total knee replacement
• Patients who have agreed to trial participation and provided written informed consent

Exclusion Criteria:

• Those who have been diagnosed with certain serious diseases that can cause knee pain. : tumor, infectious or inflammatory disease, etc.
• Those taking analgesics for the purpose of relieving pain, fever and inflammation within 7 days
• Those with progressive neurological deficits or with severe neurological symptoms
• Those who have other chronic conditions that may interfere with the interpretation of treatment effects or outcomes : Cardiovascular disease, kidney disease, diabetic neuropathy, dementia, epilepsy, etc.
• Those who are not fit or unsafe to chuna therapy: clotting disorders, Those receiving anticoagulant therapy, Severe diabetes patients who are at risk of infection, severe cardiovascular disease
• Those who are participating in other clinical trials
• Those who have a history of participating in other clinical trials within one month
• Those who are difficult to write a research consent form
• Those who are judged to be inappropriate for the clinical study by the researchers.