Evaluation of Efficacy and Safety of Single and Multiple Therapy of Herbal Medicine/Chuna Therapy on Non-specific Chronic Low Back Pain: A Study Protocol for Multicenter, 3-arm, Randomized, Single Blinded, Parallel Group, Incomplete Factorial Design, Pilot Study -

Evaluation of Efficacy and Safety of Single and Multiple Therapy of Herbal Medicine/Chuna Therapy on Non-specific Chronic Low Back Pain: A Study Protocol for Multicenter, 3-arm, Randomized, Single Blinded, Parallel Group, Incomplete Factorial Design, Pilot Study -

The Purpose of this trial is to investigate the efficacy and safety of herbal medicine with manipulation therapy on Korean Patients with Chronic Low Back Pain

Inclusion Criteria:

• Inpatients with chief complaint of low back pain in oriental rehabilitation medical center
• Age 19 - 65
• Patients who have 4 ~7 cm of VAS pain score;
• Ability to have normal communication
• Ability to give informed consent

Exclusion Criteria:

• Patients with pain duration of 3 months or less
• Patients with progressive neurologic deficit or severe neurologic symptoms by SLR test
• Patients diagnosed with serious pathology(s) which may cause low back pain (e.g. spinal metastasis of tumor(s), acute fracture, etc)
• Patients with spondylolisthesis or spondylolysis(diagnosed with grade II or higher level)
• Patients currently taking steroids, immunosuppressants, medicine for mental illness or other medication(s) that may interfere with study results
• Patients with history of spinal surgery
• Patients with more severe pain than pain caused by low back pain
• Those who do not (cannot) abide by treatment and follow up due to the mental illness such as behavior disorder, depression, anxiety neurosis etc.
• Patients with history of Medical Malpractice Case
• Patients with treatment history of low back pain within 1 month either KM or WM
• Patients participating in other clinical studies within 3 months
• Pregnant patients or patients with plans of pregnancy or lactating patients
• Patients disagree to sign the informed consent form
• Patients deemed unsuitable for participating the trial by the researchers