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This study is a pragmatic randomized controlled study that assessed 250 subjects complaining of chronic bothersome neck pain with mild discomfort in a 1:1 ratio: chuna maintenance therapy group (125 subjects, 1 time/2 weeks, total 20 weeks) and lifestyle management & self-exercise group (125 subjects, exercise method education 1 time/4 weeks, total 20 weeks).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Chuna maintenance therapy group | Experimental | This group will receive chuna therapy determined by the clinician based on the subject's symptoms, degree of improvement, etc. (1 time/2 weeks, total 20 weeks) |
|
| Lifestyle management & self-exercise group | Other | This group will perform lifestyle management and daily self-exercise. The exercise education will be performed per 4 weeks for total 20 weeks. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Chuna Maintenance Therapy | Procedure | it is conducted every two weeks for a total of 20 weeks for individuals. The technique follows the guidelines of the Society of Chuna Manual Medicine and is based on Chuna Medicine (2.5th edition), which is utilized as a textbook in Korean Medicine colleges. The treatment is selectively administered based on the clinical judgment of the practitioner. |
| Measure | Description | Time Frame |
|---|---|---|
| NRS (Numeric rating scale) | Ranging 0-10 likert scale (higher=worse) | Wk 1, 3, 5, 7, 9, 11, 13, 15, 17, 19, 21, 25 |
| NDI (Neck disability index) | Each of the 10 items scores from 0 to 5, The maximum score is 50 (higher=worse) | Wk 1, 5, 9, 13, 17, 21, 25 |
| Measure | Description | Time Frame |
|---|---|---|
| VAS(Visual analogue scale) for pain | Ranging 0-10cm scale (higher=worse) | Wk 1, 3, 5, 7, 9, 11, 13, 15, 17, 19, 21, 25 |
| Number of days with bothersome neck pain | Wk 1, 3, 5, 7, 9, 11, 13, 15, 17, 19, 21, 25 |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Bucheon Jaseng Hospital of Korean Medicine | Bucheon-si | South Korea | ||||
| Daejeon Jaseng Hospital of Korean Medicine |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41873381 | Derived | Yun JM, Kim JY, Lee SH, Lee YJ, Heo I, Shin WC, Cho JH, Seo BK, Ha IH. Multi-Institutional Pragmatic Randomized Controlled Trial to Evaluate the Effectiveness of Manual Maintenance Therapy for Chronic Bothersome Neck Pain. J Pain Res. 2026 Mar 18;19:577619. doi: 10.2147/JPR.S577619. eCollection 2026. |
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| ID | Term |
|---|---|
| D019547 | Neck Pain |
| D059350 | Chronic Pain |
| ID | Term |
|---|---|
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| Recurrence | Wk 1, 3, 5, 7, 9, 11, 13, 15, 17, 19, 21, 25 |
| PGIC (Patient Global Impression of Change) | PGIC is a 7 point scale depicting a patient's rating of overall improvement (higher=worse) | Wk 21, 25 |
| EQ-5D-5L( The 5-level EuroQol-5) | 5 items for self-rating of overall health (lower=worse) | Wk 1, 3, 5, 7, 9, 11, 13, 15, 17, 19, 21, 25 |
| HINT-8 (health-related quality of life instrument-8) | 8 items for self-rating of overall health (lower=worse) | Wk 1, 3, 5, 7, 9, 11, 13, 15, 17, 19, 21, 25 |
| Rating for Credibility and Expectancy of the treatment | Ranging 1-9 likert scale (higher=more credible, positive results are expected) | Once at screening procedure |
| Drug consumption history | Whether medication was used (Y/N) | Wk 1, 3, 5, 7, 9, 11, 13, 15, 17, 19, 21, 25 |
| Daejeon |
| South Korea |
| Haeundae Jaseng Hospital of Korean Medicine | Haeundae | South Korea |
| College of Korean Medicine, Kyung Hee University | Seoul | South Korea |
| Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Kyung Hee University | Seoul | South Korea |
| Jaseng Hospital of Korean Medicine | Seoul | South Korea |
| School of Korean Medicine, Pusan National University | Yangsan | South Korea |