Exploratory Study of Volatile Organic Compounds in Alveolar Breath

Retrospective Analysis of Volatile Organic Compounds in Alveolar Breath as Biomarkers of Idiopathic Malodor

The purpose of this secondary analysis is to identify breath signatures associated with idiopathic malodor conditions.

Individuals with metabolic disorders may sporadically produce malodors despite good hygiene. Analysis of volatile organic compounds (VOCs) helps to gain insights into medical conditions arising due to metabolic dysfunction as different metabolic pathways emit and or consume various VOCs. These VOCs can be detected via the exhaled breath collected and analyzed with a portable breath collection apparatus. VOC profiles will be compared with self-reported symptoms and other observations of participating subjects.

Inclusion Criteria:

• good general health
• willing and able to travel to one of the participating sites

Exclusion Criteria:

• medical conditions that, in the opinion of the investigator, would prevent participation
• elect not to participate in the study