Investigators asses whether there is any difference in short term recovery and long term prognosis according to the anesthetic method in patients who undergoing pancreatic cancer and bile duct cancer and undergoing surgery for PPPD or distal pancreatectomy.

Inclusion Criteria:

• Patients with ASA class I-III who are scheduled to undergo general anesthesia and who are diagnosed with pancreatic cancer or common bile duct cancer and who are scheduled for PPPD or distal pancreatectomy
• patients who voluntarily agree to participate the clinical study after fully informed and understood about the study

Exclusion Criteria:

• there was distant metastasis at the time of diagnosis
• history of drug adverse reaction or use of opioid or sedative drugs before the surgery
• patients who can not communicate enough to answer the survey
• obesity patients over BMI 30
• patient who are expected to maintain ventilator care on the first day of post operation due to the difficult to extubation right after the surgery
• patients who have inappropriate reasons to participate in clinical research

• The investigator who research the QoR-40 questionnaire before and after the surgery will not know which group the patient is assigned to.
• Because of the difference in anesthesia method, it is impossible to apply blindness to an anesthesiologist practicing anesthesia. Thus, the anesthesiologist will maintain anesthesia with the same target in both groups. (anesthesia depth, hemodynamic status and pain control)
• Blind is released to investigator and outcomes assessor after completion of QoR-40 questionnaire.