Effects of Total Intravenous Anesthesia With Propofol-remifentanil Versus Inhalational Anesthesia With Sevoflurane on Quality of Recovery in Patients Undergoing Transsphenoidal Surgery for Pituitary Tumor

A number of studies have compared the effects of total intravenous anesthesia(TIVA) versus inhalational anesthesia on perioperative period during transsphenoidal surgery. However, they have limitations especially for the phase of recovery after anesthesia: a fragmentary assessment. Quality of Recovery 40 (QoR-40) questionnaire was multi-dimensionally designed to assess the degree of recovery, specially after anesthesia and surgery. In this study, the investigators aim to compare the quality of recovery after inhalational anesthesia and after TIVA through QoR-40 questionnaire in patients undergoing transsphenoidal surgery for pituitary tumor under general anesthesia.

Inclusion Criteria:

• Patients over age 19
• Scheduled to undergo transsphenoidal surgery for pituitary tumor
• ASA class I and II

Exclusion Criteria:

• Left ventricular ejection fraction < 55%
• Third-degree atrioventricular block
• Second-degree atrioventricular block (P:QRS ratio of 3:1 or higher)
• Fever
• History of myocardial infarction, stroke or cardiac surgery within the previous 1 year
• Severe neurological disease
• Use of sedative, opioid or sleep-inducing drugs
• Allergic history of any study drug
• Pregnancy