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| Name | Class |
|---|---|
| The Hershey Company | INDUSTRY |
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The purpose of this study was to determine the effect of mid-morning gel snacks on subjective appetite, glucose and insulin responses, and food intake in healthy weight young adults.
23 (14 male, 9 female) healthy, non-smoking human subjects aged 18-30 years with a body mass index (BMI) between 20 and 24.9 were recruited in the experiment. Five gel snacks including a control snack and four modified snacks containing whey protein, oats, coconut oil or maltodextrin were tested. On six separate mornings, at least 3 days apart and after a 12 hours overnight fast, each participant consumed a standardized breakfast of cereal, milk, and orange juice at home, then arrived in the lab 2 hours after breakfast to receive one of the five test snack treatments or skip snack. Subjective appetite by a 100 mm visual analogue scale (VAS) was measured at baseline (0 min) and after each treatment up to 2 h (15, 30, 60, 90, and 120 min). Blood glucose and insulin concentrations were measured via finger-prick at the same time VAS measurements were taken. Food intake was measured via ad libitum pizza lunch.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control snack | Experimental | Participants received control snacks prepared by real fruits (pear, orange and mango) |
|
| Maltodextrin snack | Experimental | Participants received maltodextrin snacks (maltodextrin + control snack) |
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| Whey protein snack | Experimental | Participants received whey protein snacks (whey protein + control snack) |
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| Oat snack | Experimental | Participants received oat snacks (oat + maltodextrin + control snack) |
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| Coconut oil snack | Experimental | Participants received coconut oil snacks (coconut oil + control snack) |
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| Snack skipping | Experimental | Participants received snack skipping |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Control snack | Other | Isovolumetric (238.4g) gel snack prepared by real fruits (186.2kcal) |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Subjective Appetite | Participants completed subjective ratings on appetite (e.g., desire to eat, hunger, fullness, prospective food consumption) and well-being at baseline (0 min), 15, 30, 45, 60, 90, and 120 min after snack consumption, as well as immediately following lunch. | Change from baseline over 120 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| Blood Glucose Response | Blood was collected at baseline (0min), 15, 30, 45, 60, 90, and 120 min after snack consumption, as well as immediately following lunch to observe glycemic responses to gel snacks | Change from baseline over 120 minutes |
| Blood Insulin Response |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Nick Bellissimo, PhD | Toronto Metropolitan University | Principal Investigator |
| Derick Rousseau, PhD | Toronto Metropolitan University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| School of Nutrition, Ryerson University | Toronto | Ontario | M5B 2K3 | Canada |
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| ID | Term |
|---|---|
| D007333 | Insulin Resistance |
| ID | Term |
|---|---|
| D006946 | Hyperinsulinism |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
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Coded snacks in shaded tetrapaks were provided to participants
|
| Maltodextrin snack |
| Other |
Isovolumetric (238.4g) gel snack with maltodextrin (271.8kcal) |
|
| Whey protein snack | Other | Isovolumetric (238.4g) gel snack with whey protein (201.8kcal) |
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| Oat snack | Other | Isovolumetric (238.4g) gel snack with oats and maltodextrin (275.8kcal) |
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| Coconut oil snack | Other | Isovolumetric (238.4g) gel snack with coconut oil (276.4kcal) |
|
| Snack skipping | Other | no snack |
|
Blood was collected at baseline (0 min), 15, 30, 45, 60, 90, and 120 min after meal consumption, as well as immediately following lunch, to observe insulin responses to gel snacks |
| Change from baseline over 120 minutes |
| Food Intake | Participants consumed an ad libitum pizza lunch at 120 minutes | 30 min |