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The objective of this trial is to compare a snack with ingredients (whole grains and dietary fiber) to slow carbohydrate digestion to a similar control snack without such ingredients and evaluate the effect of the snack on glycemic response and subjective satiety. The test product will be compared with a control product as well as white bread in a randomized, controlled, crossover trial including 20 healthy males or females between the ages of 18 and 70 and having a body mass index (BMI) between 25 and 30 kg/m2. Following an overnight fast, participants will be given each of the study products in a random order at least a week apart. Glucose and insulin will be measured before product consumption and over a period of four hours. Visual analog scales to measure subjective satiety will also be administered over a period of four hours.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Test-cluster | Experimental | 56g of optimized savory cluster made through a proprietary process with slowly digestible carbohydrates and fiber |
|
| Control-cluster | Placebo Comparator | 56g of control cluster made from general baking process with typical ingredients commonly used in commercially available energy snacks or bars |
|
| White-bread | Placebo Comparator | 45g of white bread containing equivalent amount of available carbohydrate in 56g of optimized savory cluster |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Nutrient cluster | Other | Test cluster is an optimized savory cluster made through a proprietary baking process combined with slow digestible carbohydrates and fiber |
|
| Measure | Description | Time Frame |
|---|---|---|
| area under the curve (AUC) for glucose and insulin | 0-4 hours post consumption |
| Measure | Description | Time Frame |
|---|---|---|
| AUC for the visual analog scale (VAS) ratings of satiety | 0-4 hours post consumption |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Frank Greenway, MD | Pennington Biomedical Research Center | Principal Investigator |
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