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The present study will assess the effect of the type and timing of protein ingestion 6 days prior to, and 7 days following eccentric exercise on the time course of 1) the recovery of muscle function, 2) the recovery of perceived muscle soreness, 3) muscle metabolism.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Placebo supplement | Placebo Comparator | Post exercise placebo supplement Pre bed placebo supplement |
|
| Post exercise supplement | Active Comparator | Post exercise protein-polyphenol supplement Pre bed placebo supplement |
|
| Pre bed supplement | Active Comparator | Post exercise placebo supplement Pre bed protein-polyphenol supplement |
|
| Post exercise + pre bed supplement | Active Comparator | Post exercise protein-polyphenol supplement Pre bed protein-polyphenol supplement |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Post exercise protein-polyphenol supplement | Dietary Supplement | Participants will ingest a post exercise protein-polyphenol supplement. This will begin 6 days before eccentric exercise and will end 6 days after eccentric exercise. |
| Measure | Description | Time Frame |
|---|---|---|
| Isokinetic force production of the knee extensor muscles | 14 days |
| Measure | Description | Time Frame |
|---|---|---|
| Muscle protein synthesis | 14 days | |
| Thigh volume | 14 days | |
| Perceived muscle soreness |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Sport and Health Sciences | Exeter | Devon | EX1 2LU | United Kingdom |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33710344 | Derived | Jameson TSO, Pavis GF, Dirks ML, Lee BP, Abdelrahman DR, Murton AJ, Porter C, Alamdari N, Mikus CR, Wall BT, Stephens FB. Reducing NF-kappaB Signaling Nutritionally is Associated with Expedited Recovery of Skeletal Muscle Function After Damage. J Clin Endocrinol Metab. 2021 Jun 16;106(7):2057-2076. doi: 10.1210/clinem/dgab106. |
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| Post exercise placebo supplement | Dietary Supplement | Participants will ingest an isocaloric placebo supplement after exercise. This will begin 6 days before eccentric exercise and will end 6 days after eccentric exercise. |
|
| Pre bed protein-polyphenol supplement | Dietary Supplement | Participants will ingest a protein-polyphenol supplement before bed. This will begin 6 days before eccentric exercise and will end 6 days after eccentric exercise. |
|
| Pre bed placebo supplement | Dietary Supplement | Participants will ingest an isocaloric placebo supplement before bed. This will begin 6 days before eccentric exercise and will end 6 days after eccentric exercise. |
|
| 14 days |
| Isometric force production of the knee extensor muscles | 14 days |