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| Name | Class |
|---|---|
| Beachbody | INDUSTRY |
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This study will assess the effect of daily post-exercise vegan (pea) and animal (whey) protein ingestion compared to placebo over 7 days of recovery from strenuous exercise. Muscle strength and soreness will be measured daily, and mechanisms underpinning recovery will be investigated in muscle biopsies taken 3, 24 and 48 hours after exercise.
Strenuous exercise can cause muscle soreness and reduced muscle strength. It is widely acknowledged that nutritional supplements derived from animal protein sources, including whey from milk, aids recovery when taken immediately after strenuous exercise. However, the effect of vegan protein supplements are less understood, and how they affect recovery of strength and soreness is not known. This is an important area of research due to the increasing demand for plant-based protein.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Animal Protein | Active Comparator |
| |
| Vegan Protein | Active Comparator |
| |
| Placebo | Placebo Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Recovery animal (20g whey) protein supplement | Dietary Supplement | Animal protein supplement consumed post exercise to aid recovery of muscle function following strenuous exercise. |
| Measure | Description | Time Frame |
|---|---|---|
| Change in isokinetic work (W30) performed before and every 24 h after performing 300 maximal eccentric quadriceps contractions. | The recovery of skeletal muscle isokinetic force production following eccentric exercise using an isokinetic dynamometer | Once per 24 hour period for 7 days |
| Measure | Description | Time Frame |
|---|---|---|
| Perceived quadriceps muscle soreness | Soreness will be assessed using a visual analogue scale (VAS) to determine whether the protein supplement can reduce muscle soreness following eccentric exercise. This scale will represent a 100mm line with no pain and worst pain anchored at either end of the scale. | Once per 24 hour period for 7 days |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Francis Stephens | University of Exeter | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Exeter | Exeter | EX1 1TX | United Kingdom |
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| ID | Term |
|---|---|
| D000067796 | Whey |
| C008315 | maltodextrin |
| ID | Term |
|---|---|
| D008892 | Milk |
| D001628 | Beverages |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
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| Recover vegan (26g pea) protein supplement | Dietary Supplement | Vegan protein supplement consumed post exercise to aid recovery of muscle function following strenuous exercise. |
|
| Placebo (32g maltodextrin) | Dietary Supplement | Placebo consumed post exercise to aid recovery of muscle function following strenuous exercise. |
|
| Muscle swelling |
Determine whether the protein supplement can reduce muscle swelling following eccentric exercise assessed using MRI |
| Once per 24 hour period for 3 days |
| Rate of protein incorporation into the muscle | Determine whether the strenuous exercise and a protein supplement can upregulate protein synthesis following strenuous exercise assessed by muscle biopsies | Once per 24 hour period for 3 days |
| Plasma creatine kinase (CK) activity before and every 24 h after performing 300 maximal eccentric quadriceps contractions. | Damage and inflammatory bio markers following strenuous exercise assessed by blood sample | Once per 24 hour period for 7 days |
| Change in flow mediated dilation | Determine whether the protein polyphenol supplement can impact vascular function following eccentric exercise | Once hourly post exercise for 3 hours |
| D003611 |
| Dairy Products |
| D005502 | Food |
| D019602 | Food and Beverages |