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| Name | Class |
|---|---|
| PepsiCo Global R&D | INDUSTRY |
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Assess impact of potato phytochemical on post-prandial gastric emptying and glucose release from products in a pilot human study.
Preclinical data obtained using an Caco-2 intestinal cell model and enzyme assays suggest phenolic-rich potato extracts decrease intestinal glucose transport. The aim is to determine if these effects extend to the the an in vivo situation. Specifically, the glycemic response following consumption of phenolic rich pigmented potatoes compared to white potatoes with lower phenolic content will be measured. Gastric emptying will also be measured to show the effects are in fact due to rate of carbohydrate digestion and intestinal glucose transport and not gastric emptying rate.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Purple Majesty potato chips | Experimental | Purple Majesty potato chips |
|
| Mountain Rose potato chips | Experimental | Mountain Rose potato chips |
|
| White potato chips | Experimental | White potato chips |
|
| Crackers | Experimental | Crackers |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Purple Majesty potato chips | Other | Purple Majesty potato chips |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Blood Glucose | blood taken at 10, 20, 30, 60, and 120 minutes by finger prick | up to 2 hours |
| Gastric emptying | Breath Hydrogen concentrations will be measured every 15 minutes for 4 hours | up to 4 hours |
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Inclusion Criteria:
Exclusion Criteria:
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| Mountain Rose potato chips |
| Other |
Mountain Rose potato chips |
|
| White potato chips | Other | White potato chips |
|
| Crackers | Other | Crackers |
|