Pilot Assessment of Continuous Glucose Monitor for Post-meal Glucose Responses to Herbs and Spices.

Glucosidase Inhibitors and Glucose Metabolism

The purpose of this study is to determine whether continuous glucose monitoring is sensitive to quantifying the glucose response related to consumption of a starchy vegetable (potato) in combination with or separate from consumption of herbs and spices at the same meal.

This is a pilot study which will enroll a maximum of 10 participants. There will be 3 different food entree preparations that participants will consume (1 entree per day within the 10 day period). The order in which participants eat the different entrees will be randomized. The 3 different food entree preparations are as follows: 1) prepared potato entree with no herbs and spices, 2) prepared potato entree paired with herbs and spices, 3) prepared potato entree with herbs and spices consumed at a subsequent meal.

Following enrollment, participants will be randomized to the order of entree preparation types and provided all of the entrees with the instructions for food preparation and order of consumption noted when they arrive at the scheduled study visit. The entrees will be standardized for caloric content, composition, and preparation method. Post-consumption glucose responses will be recorded by continuous glucose monitors, which will be provided to participants at the first study visit.

Inclusion Criteria:

• body mass index (BMI): 20-35
• no dietary restriction or food allergies to study items
• weight stable
• access to a smart phone
• willingness to wear a continuous glucose monitor for the duration of the study (at minimum 10 days)

Exclusion Criteria:

• pregnancy or anticipating pregnancy or lactation
• food allergy to study items
• diagnosed diabetes (type 1 or 2) or taking diabetes medications
• history of bariatric surgery
• consumed >1 serving of potatoes daily before enrollment
• 5% weight loss or gain within the past 6 months
• medical conditions or medication that would prevent the ability to comply with the treatment assignment and/or affect blood glucose or energy balance
• condition which would prevent the ability to wear a continuous glucose monitor on the upper arm for the study duration