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A randomized, single-blind cross-over clinical nutrition trial will be conducted. The effects of yellow-fleshed potatoes and yellow-fleshed potatoes supplemented with anthocyanins extracted from purple-fleshed potatoes on healthy men's postprandial glycemia and insulinemia will be compared. Additionally, the postprandial metabolism and metabolites, and the appearance and metabolism of the flavonoids and their metabolites is studied in plasma, urine and feces.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Anthocyanins and yellow potato | Experimental | 168 mg of anthocyanins extracted from purple-fleshed potatoes added to 350 g of steam-cooked mashed potatoes in water |
|
| Yellow potato | Experimental | 350 g of steam-cooked mashed potatoes in water |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Dietary | Other |
|
| Measure | Description | Time Frame |
|---|---|---|
| Plasma glucose concentration | 0min, 20min, 40min, 60min, 90min, 120min, 180min, 240min | |
| Plasma insulin concentration | 0min, 20min, 40min, 60min, 90min, 120min, 180min, 240min |
| Measure | Description | Time Frame |
|---|---|---|
| Concentrations and quality of metabolites and flavonoid color compounds and their metabolites in plasma (NMR and (U)HPLC-MS/MS measurements) | 0min, 20min, 40min, 60min, 90min, 120min, 180min, 240min | |
| Concentrations and quality of metabolites and flavonoid color compounds and their metabolites in urine (NMR and (U)HPLC-MS/MS measurements) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Kaisa M Linderborg, PhD | Department of Biochemistry, University of Turku | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Biochemistry, University of Turku | Turku | 20014 | Finland |
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| ID | Term |
|---|---|
| D004032 | Diet |
| ID | Term |
|---|---|
| D009747 | Nutritional Physiological Phenomena |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
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| Before meal, and 0-4h, 4-8h, 8-16h, 16-24 h |
| Concentrations and quality of metabolites and flavonoid color compounds and their metabolites in feces (NMR and (U)HPLC-MS/MS measurements) | before and after meal |
| Area under the glucose concentration curve (AUC) | 0min, 20min, 40min, 60min, 90min, 120min, 180min, 240min |
| Area under the insulin concentration curve (AUC) | 0min, 20min, 40min, 60min, 90min, 120min, 180min, 240min |