Navigation and Free Recall in Chronically Implanted Humans

Memory, Epilepsy and Brain Stimulation: Oscillatory Patterns During Real-world Navigation and Free Recall in Chronically Implanted Humans

This study is designed to identify brain activity associated with good memory in subjects with a chronically implanted RNS® device and to study the effects of therapeutic stimulation for epilepsy on memory. This will be accomplished through analysis of ECoG data collected during memory encoding for short and long-term free recall as well as during navigation tasks.

Inclusion Criteria:

• able to give informed consent
• 18 years of age or older
• Diagnosis of epilepsy
• Implanted RNS® device and receiving therapeutic stimulation for epilepsy.
• Capable of completing experimental tasks in the judgment of the Principal Investigator

Exclusion Criteria:

• RNS® Neurostimulator implanted within 3 months of experimental tasks.