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To describe the effect and mechanisms of action faba bean powder and fractions (protein, starch and fiber) on glucose and insulin homeostasis, food intake, satiety and metabolic regulation in young adults (18 to 30 years).
The overall objective is to describe the effect and mechanisms of action of faba bean powder and fractions (protein, starch and fiber) on glucose and insulin homeostasis, food intake, satiety and metabolic regulation in young adults (18 to 30 years). The specific objectives are to test the acute effects of different faba bean ingredient smoothie on: 1) post-prandial blood glucose, appetite, satiety hormone and insulin for 200 minutes, and 2) food intake 120 minutes following consumption of the faba bean smoothie. Two short-term acute studies will be conducted to meet these objectives. Both acute studies will follow a randomized, double blinded, balanced, repeated measures design and the same protocol; except one will have an ad libitum pizza meal (study 1), while the other will have a fixed pizza meal (study 2) at 120 minutes. Half the participants will have blood drawn by IV and the other half will be finger prick.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control smoothie | Placebo Comparator | Control smoothie with 32 g corn maltodextrin without added faba bean fractions. |
|
| Faba Bean powder smoothie | Experimental | Breakfast smoothie with 32 g whole faba bean powder. |
|
| Faba bean protein concentrate smoothie | Experimental | Breakfast smoothie with 32 g faba bean protein concentrate. |
|
| Faba bean starch smoothie | Experimental | Breakfast smoothie with 33 g faba bean starch. |
|
| Faba bean protein isolate smoothie |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Faba bean powder smoothie | Other | Breakfast smoothie with 32 g whole faba bean powder (300g). |
|
| Measure | Description | Time Frame |
|---|---|---|
| blood glucose | measured by finger prick blood samples by glucose meters | 0-200 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| appetite | measured by VAS questionnaire | 0-200 minutes |
| satiety hormones | measured by enzyme-linked immunosorbent assay (ELISA) | 0- 200mins |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Richardson Centre for Functional Foods and Nutraceuticals | Winnipeg | Manitoba | R3T 2N2 | Canada |
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| Experimental |
Breakfast smoothie with 32 g faba bean protein isolate. |
|
| Faba bean protein concentrate smoothie | Other | Breakfast smoothie with 32 g faba bean protein concentrate. |
|
| Faba bean starch smoothie | Other | Breakfast smoothie with 33 g faba bean starch. |
|
| Faba bean protein isolate smoothie | Other | Breakfast smoothie with 32 g faba bean protein isolate. |
|
| Non-pulse smoothie smoothie | Other | Control smoothie with 32 g corn maltodextrin without added faba bean fractions. |
|
| insulin | measured by ELISA | 0-200mins |
| food intake | energy intake at ad-libitum pizza meal | 120 minutes following consumption of the faba bean smoothie |
| physical comfort | measured by VAS questionnaire | 0-200 minutes |
| energy/fatigue | measured by VAS questionaire | 0-200 minutes |
| ID | Term |
|---|---|
| D007333 | Insulin Resistance |
| ID | Term |
|---|---|
| D006946 | Hyperinsulinism |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
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