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The aim of this study is to determine the effects of bean physical form (whole versus blended) and Beano on postprandial responses. The postprandial responses the investigators will examine include blood glucose, appetite, metabolic rate, physical symptoms, and mood. To accomplish this aim the investigators will conduct a randomized, placebo-controlled trial in overweight and obese but otherwise healthy (non-diabetic) men and women
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| alpha-gal & blended lentils | Experimental | 3 capsules of alpha-gal taken with blended lentils |
|
| alpha-gal & whole lentils | Experimental | 3 calpsules of alpha-gal taken with whole lentils |
|
| alpha-gal & no lentils | Experimental | 3 capsules of alpha-gal taken with no lentils control |
|
| Placebo & blended lentils | Placebo Comparator | 3 capsules of placebo taken with blended lentils |
|
| Placebo & whole lentils | Placebo Comparator | 3 capsules of placebo taken with whole lentils |
|
| Placebo & no lentils | Placebo Comparator | 3 capsules of placebo taken with no lentils control |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| blended lentils | Other | blended lentils burritto breakfast |
|
| Measure | Description | Time Frame |
|---|---|---|
| Appetite | Subjects were given an appetite questionnaire to complete at time 0, 20, 40, 60, 120 and 180 | 3 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Blood glucose | Finger prick blood were taken at time 0, 20, 40, 60, 120 and 180 for glucose measurement using a glucometer | 3 hours |
| fasting and postprandial energy expentidure | Fasting energy expenditure was measured for thirty minutes before meal and beano intervensions were given and at postprandial time points 20, 40, 60, 120 and 180, postprandial energy expenditure was measured for 15 minutes at each time point |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Purdue University | West Lafayette | Indiana | 47907 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25411033 | Derived | Anguah KO, Wonnell BS, Campbell WW, McCabe GP, McCrory MA. A blended- rather than whole-lentil meal with or without alpha-galactosidase mildly increases healthy adults' appetite but not their glycemic response. J Nutr. 2014 Dec;144(12):1963-9. doi: 10.3945/jn.114.195545. Epub 2014 Oct 8. |
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|
| whole lentils | Other | whole lentils breakfast burritto |
|
| no lentils | Other | No lentils control breakfast burritto |
|
| 4 hours |
| gastrointestinal symptoms | At timepoints 0, 20, 40, 60, 120 and 180, gastroinstinal symptoms were assessed using a questionnaire | 3 hours |