Fate of Nutrient-Derived Amino Acids, FONDAA

Fate of Nutrient-Derived Amino Acids: Influence of Habituated Levels of Daily Dietary Protein Intake on Protein Utilization

12 elderly (65-70 years of age) male subjects will be included and complete a double blinded cross-over study. They will be habituated for 21 days to either low or high protein intake (below 0.8 g/kg or above 1.5 g/kg, respectively). Following a 45 day washout period they will switch to the alternate group. At the end of each habituation period, the investigators will measure the appearance of labelled amino acids from milk proteins.

Exclusion Criteria:

• Hyperlipidemia
• Hypertension

Inclusion Criteria:

• Males age 65-70
• Independently dwelling
• Without any major health issues (blood pressure, cholesterol and lipid profile will be measured and evaluated by a physician)
• Non-diabetic
• No organ disease
• No back pain
• Not regularly take any prescription drugs or dietary supplements, which can influence muscle protein synthesis
• Alcohol intake below 21 units pr. week
• No known arthrosclerosis