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To evaluate the effects of flaxseed supplementation on fasting blood sugar, lipid profile and anthropocentric measurements in subjects with metabolic syndrome, in a randomized, open-labeled, controlled pilot study, 44 subjects with metabolic syndrome will be received 30g/d flaxseed with lifestyle modification or lifestyle modification alone for 12 weeks. Both groups will be advised to follow an energy balanced diet and physical activity recommendations. Parameters related to metabolic syndrome will be measured at the baseline and at the end of the study.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Flaxseed | Experimental | 30 g milled brown flaxseed + lifestyle modification |
|
| control | Active Comparator | lifestyle modification including dietary and physical activity recommendation |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| flaxseed | Dietary Supplement |
| ||
| lifestyle modification |
| Measure | Description | Time Frame |
|---|---|---|
| Insulin resistance index (HOMA-IR) | The homeostatic model assessment (HOMA) | 12 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| ID | Term |
|---|---|
| D024821 | Metabolic Syndrome |
| ID | Term |
|---|---|
| D007333 | Insulin Resistance |
| D006946 | Hyperinsulinism |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
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| ID | Term |
|---|---|
| D008043 | Linseed Oil |
| ID | Term |
|---|---|
| D005224 | Fats, Unsaturated |
| D005223 | Fats |
| D008055 | Lipids |
| D010938 | Plant Oils |
| D009821 |
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|
| D009750 |
| Nutritional and Metabolic Diseases |
| Oils |
| D028321 | Plant Preparations |
| D001688 | Biological Products |
| D045424 | Complex Mixtures |