Same-day Cervical Preparation With Misoprostol Before Hysteroscopy

Same-day Cervical Preparation With Misoprostol Before Hysteroscopy: a Randomized Trial of Different Routes of Administration

This is a randomized trial, assessing Misoprostol efficacy in cervical preparation several hours prior to hysteroscopy, comparing the different routes of administration (PO/PV/buccal). Initial cervical dilatation will be assessed, as well as surgical ease of dilatation, time required to achieve dilatation and patient preference.

Inclusion Criteria:

• Patients admitted for elective hysteroscopy (diagnostic/surgical) at Wolfson Medical Center
• Written consent supplied

Exclusion Criteria:

• Contraindications to prostaglandin treatment (severe asthma, glaucoma, severe cardiac disease, renal failure)
• Prostaglandin allergy
• Pregnancy
• Genital infection
• Space-occupying lesion in the endocervical canal
• Prior cervical surgery