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| Name | Class |
|---|---|
| Agriculture and Agri-Food Canada | OTHER_GOV |
| Pulse Canada | OTHER |
| Saskatchewan Pulse Growers | OTHER |
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The purpose of this study is to assess the effects of consuming various lentil varieties in mixed-meals (containing either white rice or white potato) on post-prandial blood glucose and insulin as compared to white rice or white potato alone.
Eligible participants will undergo a total of 6 study visits. During each visit, a fasted blood sample will be taken by fingerprick, and approximately 500µL of blood will be dripped into a collection tube. The participant will then consume a meal of either: white bread, white rice (or white potato), or white rice with lentils (or white potato with lentils). White bread will be consumed on the first study visit and the rest of the meals will take place in random order in the visits following. Each meal will provide a total of 50g available carbohydrate. Six more blood samples will be taken by fingerprick at 15, 30, 45, 60, 90 and 120 minutes after the beginning of the meal.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| White bread | Experimental |
| |
| Lentil 1 + white rice | Experimental |
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| Lentil 2 + white rice | Experimental |
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| Lentil 3 + white rice | Experimental |
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| White rice | Experimental |
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| Lentil 1 + potato | Experimental |
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| Lentil 2 + potato | Experimental |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Various lentil varieties (varying in slow digested starch content) | Other | Randomized, cross-over block design. Comparison of glycemic and insulinemic responses following meals composed of:
Participants with be assigned to either the white rice or white potato group. Meals will provide 50g available carbohydrate (AC). In meals containing lentils, whole cooked lentils will provide 25g AC either white rice or white potato will provide 25g AC. Meals will be randomly consumed across 6 study visits, with 2 white bread control meals (one of which will take place on the first visit). |
| Measure | Description | Time Frame |
|---|---|---|
| Postprandial blood glucose | Different meals will be consumed on separate occasions over 3-6 week period. | Acute- 2 hours following meal |
| Postprandial blood insulin | Different meals will be consumed on separate occasions over 3-6 week period. | Acute- 2 hours following meal |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Alison M Duncan, Ph.D, R.D | University of Guelph | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Human Nutraceutical Research Unit | Guelph | Ontario | N1G 2W1 | Canada |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 29659967 | Derived | Moravek D, Duncan AM, VanderSluis LB, Turkstra SJ, Rogers EJ, Wilson JM, Hawke A, Ramdath DD. Carbohydrate Replacement of Rice or Potato with Lentils Reduces the Postprandial Glycemic Response in Healthy Adults in an Acute, Randomized, Crossover Trial. J Nutr. 2018 Apr 1;148(4):535-541. doi: 10.1093/jn/nxy018. |
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| ID | Term |
|---|---|
| D003920 | Diabetes Mellitus |
| ID | Term |
|---|---|
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D004700 | Endocrine System Diseases |
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| Lentil 3 + potato | Experimental |
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| Potato | Experimental |
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