Dual Trigger Versus Booster Dose of HCG

Dual Trigger Versus Booster Dose of HCG on Ovum Pickup Day in Antagonist IVF/ICSI Cycles Triggered With GnRH Agonist in High Responder Females to Salvage the Luteal Phase

To salvage the luteal phase and improve pregnancy rate in antagonist IVF/ICSI cycles triggered with GnRH agonist. Two strategies are compared dual trigger with GnRH agonist plus 1000 IU of HCG or triggering with GnRH and giving a booster dose of HCG (1500 IU) on the day of ovum pickup.

Inclusion Criteria:

• High responder females undergoing antagonist protocol IVF/ICSI cycle
• More than 14 MII oocytes
• Estradiol more than 3500 pg/ml on day of trigger

Exclusion Criteria:

• Any other protocol
• Normal or poor responders