Three Small Doses of HCG Versus Booster Dose of HCG on Ovum Pickup Day

Supplementing the Luteal Phase With Three Small Doses of HCG Versus Booster Dose of HCG on Ovum Pickup Day in Antagonist IVF/ICSI Cycles Triggered With GnRH Agonist in High Responder Females to Salvage the Luteal Phase

To salvage the luteal phase and improve pregnancy rate in antagonist IVF/ICSI cycles triggered with GnRH agonist. Two strategies are compared supplementing the luteal phase with three small doses (500 IU) of HCG and giving a booster dose of HCG (1500 IU) on the day of ovum pickup.

Inclusion Criteria:

• High responder females undergoing antagonist protocol IVF/ICSI cycle
• More than 14 MII oocytes
• Estradiol more than 3500 pg/ml on day of trigger

Exclusion Criteria:

• Any other protocol
• Normal or poor responders