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| ID | Type | Description | Link |
|---|---|---|---|
| 2013005 | Other Grant/Funding Number | Clinical Research Program 5010 of Sun Yat-sen University |
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Recent clinical experience showed that laparoscopic hepatectomy has advantages of minimally invasive compared to open liver resection, however, laparoscopic liver resection is still difficult and risky. Currently it is only carried out in a few large medical centers with slow development. The related research studies were retrospective analysis, there were no prospective randomized controlled multi-center study reported. Because of its relatively simple anatomical advantages, left liver seems to be as the best platform to ensure maximum safety and feasibility of prospective randomized study for laparoscopic hepatectomy .This project intends to carry out a prospective randomized controlled multi-center study to look for evidence of safety, efficacy and minimally invasive of laparoscopic left liver resection, evaluate the long-term efficacy including overall survival, disease-free survival as well as time to disease recurrence for the left liver carcinoma.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| laparoscopic hepatectomy | Other | laparoscopic hepatectomy |
|
| open liver resection | Other | open liver resection |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| laparoscopic hepatectomy | Procedure |
| ||
| open liver resection |
| Measure | Description | Time Frame |
|---|---|---|
| amount of bleeding | Participants will be observed for the duration of hospital stay, an expected average of 4 weeks. | |
| time of operation | Participants will be observed for the duration of hospital stay, an expected average of 4 weeks. | |
| status of the resection margins | Participants will be observed for the duration of hospital stay, an expected average of 4 weeks. | |
| bile leakage | Participants will be observed for the duration of hospital stay, an expected average of 4 weeks. | |
| abdominal adhesion | Participants will be observed for the duration of hospital stay, an expected average of 4 weeks. |
| Measure | Description | Time Frame |
|---|---|---|
| overall survival | Participants will be followed for 5 years. | |
| disease-free survival | Participants will be followed for 5 years. | |
| time to disease recurrence |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ya-Jin Chen, M.D. | Contact | 00862034071169 | drcaojun@163.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Sun Yat-sen Memorial Hospital,Sun Yat-sen University | Recruiting | Guangzhou | Guangdong | 510120 | China |
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| ID | Term |
|---|---|
| D006528 | Carcinoma, Hepatocellular |
| ID | Term |
|---|---|
| D000230 | Adenocarcinoma |
| D002277 | Carcinoma |
| D009375 | Neoplasms, Glandular and Epithelial |
| D009370 | Neoplasms by Histologic Type |
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| Procedure |
|
| Participants will be followed for 5 years. |
| D009369 | Neoplasms |
| D008113 | Liver Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
| D004066 | Digestive System Diseases |
| D008107 | Liver Diseases |