Surgical Specification and Efficacy Evaluation of Total Laparoscopic Left Liver Resection

Recent clinical experience showed that laparoscopic hepatectomy has advantages of minimally invasive compared to open liver resection, however, laparoscopic liver resection is still difficult and risky. Currently it is only carried out in a few large medical centers with slow development. The related research studies were retrospective analysis, there were no prospective randomized controlled multi-center study reported. Because of its relatively simple anatomical advantages, left liver seems to be as the best platform to ensure maximum safety and feasibility of prospective randomized study for laparoscopic hepatectomy .This project intends to carry out a prospective randomized controlled multi-center study to look for evidence of safety, efficacy and minimally invasive of laparoscopic left liver resection, evaluate the long-term efficacy including overall survival, disease-free survival as well as time to disease recurrence for the left liver carcinoma.

Inclusion Criteria:

• Child-pugh A-B
• Primary hepatocellular carcinoma of the left liver lobe
• Tumor size ≤5cm in diameter
• KPS≥60

Exclusion Criteria:

• Significant abnormal liver function
• Significant abnormal Heart function
• Significant abnormal lung function
• Significant abnormal kidney function