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The aim of this study is to evaluate whether supplementation with resistant starch improves biomarkers associated with antioxidant status and insulin resistance in subjects with overweight and obesity.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Hi-maize resistant starch | Experimental | 13.5 g/day |
|
| Maltodextrin | Placebo Comparator | 13.5 g/day |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Hi-maize resistant starch | Dietary Supplement | 13.5 g/day |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Antioxidant status | Superoxide dismutase (SOD), Plasma malondialdehyde (MDA), Total antioxidant capacity (TAC) | 4 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Insulin resistance | Fasting glucose, Fasting insulin, Insulin resistant (HOMA-IR) | 4 weeks |
| Lipid profile | Triglyceride, Total cholesterol, HDL-cholesterol, LDL-cholesterol, Total cholesterol/HDL-cholesterol |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Mohammad Alizadeh, PhD | Assistant Professor in Nutrition | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Urmia | Azerbaijan-gharbi | Iran |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31720257 | Derived | Eshghi F, Bakhshimoghaddam F, Rasmi Y, Alizadeh M. Effects of Resistant Starch Supplementation on Glucose Metabolism, Lipid Profile, Lipid Peroxidation Marker, and Oxidative Stress in Overweight and Obese Adults: Randomized, Double-Blind, Crossover Trial. Clin Nutr Res. 2019 Oct 28;8(4):318-328. doi: 10.7762/cnr.2019.8.4.318. eCollection 2019 Oct. |
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| ID | Term |
|---|---|
| D050177 | Overweight |
| D009765 | Obesity |
| D007333 | Insulin Resistance |
| ID | Term |
|---|---|
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
| D001835 | Body Weight |
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| ID | Term |
|---|---|
| C572111 | high-amylose maize type 2 resistant starch, maize |
| C008315 | maltodextrin |
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| Maltodextrin |
| Dietary Supplement |
13.5 g/day |
|
| 4 weeks |
| Blood pressure | 4 weeks |
| Anthropometric parameters | Height, Weight, Body Mass Index (BMI), Waist circumference | 4 weeks |
| D012816 |
| Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D006946 | Hyperinsulinism |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |