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The purpose of this study is to determine the effects of a dietary fiber, resistant starch, on insulin sensitivity. Low insulin sensitivity is a risk factor for some diseases including type 2 diabetes and heart disease. This study will show if consuming resistant starch can help improve insulin sensitivity in overweight and obese people.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Hi-maize starch (Low dose) | Other | resistant starch | ||
| Hi-maize starch (High-dose) | Other | resistant starch | ||
| Control (starch) | Other | rapidly digestible starch |
| Measure | Description | Time Frame |
|---|---|---|
| insulin sensitivity | 4 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Inflammatory markers, glycemia, serum lipids | 4 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Provident Clinical Research and Consulting, Inc | Glen Ellyn | Illinois | 60137 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 22357745 | Derived | Maki KC, Pelkman CL, Finocchiaro ET, Kelley KM, Lawless AL, Schild AL, Rains TM. Resistant starch from high-amylose maize increases insulin sensitivity in overweight and obese men. J Nutr. 2012 Apr;142(4):717-23. doi: 10.3945/jn.111.152975. Epub 2012 Feb 22. |
| Label | URL |
|---|---|
| Related Info | View source |
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| ID | Term |
|---|---|
| D007333 | Insulin Resistance |
| ID | Term |
|---|---|
| D006946 | Hyperinsulinism |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
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| ID | Term |
|---|---|
| D013213 | Starch |
| ID | Term |
|---|---|
| D005936 | Glucans |
| D001704 | Biopolymers |
| D011108 | Polymers |
| D046911 | Macromolecular Substances |
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| D004040 |
| Dietary Carbohydrates |
| D002241 | Carbohydrates |
| D011134 | Polysaccharides |