Effects of Resistant Starch in a Baked Snack Bar on a Post-prandial Glycemic and Insulinemic Response
Effects of Resistant Starch in a Baked Snack Bar on a Post-prandial Glycemic and Insulinemic Response
ClinicalTrials.gov ID
NCT02187913
Lead Sponsor
Purdue UniversityOTHER
Overall Status
Unknown status
Study Type
Interventional
Phase
Not Applicable
Enrollment
20Estimated
Last Update Posted
Jul 11, 2014Estimated
Start Date
Jul 2014
Primary Completion Date
Dec 2014Estimated
Official Title
Effects of Resistant Starch in a Baked Snack Bar on a Post-prandial Glycemic and Insulinemic Response
Brief Summary
About two-thirds of adults in the United States are overweight or obese which can cause adverse health consequences for those individuals. Post-prandial hyperglycemia is one of these possible consequences and is associated with a higher risk for Type 2 Diabetes. Controlling hyperglycemia is important in the prevention of the onset of diabetes and obesity. Resistant starch is a dietary carbohydrate which is not completely digested in the gut and produces energy for the body to use. The investigators are interested in assessing the effects of resistant starch on postprandial blood glucose and insulin concentrations.
Aim: To assess the effects of a resistant starch on post-prandial blood glucose and insulin concentrations.
Hypothesis: A baked snack bar with a resistant starch will blunt and sustain the post-prandial rise in blood glucose and insulin concentrations compared to a baked snack bar with maltodextrin (an easily digested carbohydrate).
Hyperglycemia, Diabetes, and Obesity
Resistant starch
Ages Eligible for Study
Adult (18-64)
Sexes Eligible for Study
All
Accepts Healthy Volunteers
Yes
Eligibility Criteria
Inclusion Criteria:
Thirty healthy men and women (aged 18-29y) will be recruited from the greater Lafayette, IN region with the expectation that ≥20 subjects will complete the study. Subjects must weigh >110 pounds, with a BMI between 20.0 and 29.9.
Exclusion Criteria:
Weight change > 3kg in the past 3 months
Exercising vigorously over the past 3 months as well as no exercise 3 days prior to testing day
Intestinal disorders including lipid mal-absorption or lactose intolerance
Abnormal liver or kidney function tests; fasting blood glucose >100mg/dL
Smoking
Drinking more than 2 alcoholic drinks per day
Taking lipid-lowering medications or dietary supplements affecting plasma cholesterol concentration.