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| Name | Class |
|---|---|
| Dairy Research Institute | OTHER |
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Blood sugar and insulin levels after a meal may be altered by the food and beverages a person consumes. Keeping a healthy blood sugar level may help prevent and manage type 2 diabetes and related diseases. This study will look at how drinking different common beverages (milk, low-fat milk, nonfat milk, orange juice, coffee, and water) with a meal changes blood sugar and insulin levels.
The broad aim of the proposed research is to evaluate the effects of consuming milk and non-milk beverages with a breakfast meal on postprandial glucose and insulin responses in overweight and obese adults with varying levels of glucose tolerance (normal, pre-diabetic, type 2 diabetes). The investigators expect the consumption of fluid milk with breakfast to decrease the postprandial glucose response relative to other non-milk beverages (orange juice and sweetened coffee). Furthermore, the investigators expect that there will be no difference in the postprandial glucose or insulin response between varieties of fluid milk (skim, low-fat, and whole).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Acute beverage (Water) consumption | Experimental | Acute beverage (Water)consumption with breakfast measuring blood glucose and insulin levels at specific time points. consumption with breakfast measuring blood glucose and insulin levels at specific time points. |
|
| Acute beverage (Black Coffee) consumption | Experimental | Acute beverage (Black Coffee)consumption with breakfast measuring blood glucose and insulin levels at specific time points. consumption with breakfast measuring blood glucose and insulin levels at specific time points |
|
| Acute beverage (Orange Juice) consumption | Experimental | Acute beverage (Orange Juice)consumption with breakfast measuring blood glucose and insulin levels at specific time points. consumption with breakfast measuring blood glucose and insulin levels at specific time points |
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| Acute beverage (Whole Milk) consumption | Experimental | Acute beverage (Whole Milk) consumption with breakfast measuring blood glucose and insulin levels at specific time points. consumption with breakfast measuring blood glucose and insulin levels at specific time points |
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| Acute beverage (2% Milk) consumption |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Acute beverage (water) consumption | Other | Acute beverage consumption includes water. |
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| Measure | Description | Time Frame |
|---|---|---|
| plasma glucose levels | Subjects will come to testing once a week for six weeks. Each testing day, subject will come in fasted, and a fasting blood draw will be taken. Subjects will then be fed a standard breakfast with one of the 6 beverages (coffee sweetened with sugar, orange juice, water, whole milk, skim milk, low fat milk). Blood will be taken at 30, 60, 60, 90, 120, 150,180,210,240 minutes after the meal. | 6 mornings separated by at least a week, fasting and 30, 60, 60, 90, 120, 150,180,210,240 minutes postprandial |
| Measure | Description | Time Frame |
|---|---|---|
| Plasma Insulin Levels | Subjects will come to testing once a week for six weeks. Each testing day, subject will come in fasted, and a fasting blood draw will be taken. Subjects will then be fed a standard breakfast with one of the 6 beverages (coffee sweetened with sugar, orange juice, water, whole milk, skim milk, low fat milk). Blood will be taken at 30, 60, 60, 90, 120, 150,180,210,240 minutes after the meal. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Wayne Campbell, PhD | Purdue University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Purdue University | West Lafayette | Indiana | 47906 | United States |
| Type | Date | Date Unknown |
|---|---|---|
| Release | Feb 23, 2024 | |
| Reset | Jul 31, 2024 |
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| Experimental |
Acute beverage (2% Milk) consumption with breakfast measuring blood glucose and insulin levels at specific time points. consumption with breakfast measuring blood glucose and insulin levels at specific time points |
|
| Acute beverage (Skim Milk) consumption | Experimental | Acute beverage (Skim Milk)consumption with breakfast measuring blood glucose and insulin levels at specific time points. consumption with breakfast measuring blood glucose and insulin levels at specific time points |
|
| Acute beverage (Black Coffee) consumption | Other | Acute beverage consumption includes black coffee. |
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| Acute beverage (Orange Juice) consumption | Other | Acute beverage consumption includes Orange Juice.. |
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| Acute beverage (Whole Milk) consumption | Other | Acute beverage consumption includes whole milk |
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| Acute beverage (2% Milk) consumption | Other | Acute beverage consumption includes 2% milk |
|
| Acute beverage (Skim Milk) consumption | Other | Acute beverage consumption includes skim milk |
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| 6 mornings separated by at least a week, fasting and 30, 60, 60, 90, 120, 150,180,210,240 minutes postprandial |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Feb 23, 2024 | Jul 31, 2024 |
| ID | Term |
|---|---|
| D014867 | Water |
| D004467 | Economics |
| D008892 | Milk |
| ID | Term |
|---|---|
| D006878 | Hydroxides |
| D000468 | Alkalies |
| D007287 | Inorganic Chemicals |
| D000838 | Anions |
| D007477 | Ions |
| D004573 | Electrolytes |
| D010087 | Oxides |
| D017601 | Oxygen Compounds |
| D004472 | Health Care Economics and Organizations |
| D001628 | Beverages |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
| D003611 | Dairy Products |
| D005502 | Food |
| D019602 | Food and Beverages |
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