Active, not recruitingInterventionalNot ApplicableUpdated Apr 13, 2026
Bioefficacy of Phenolic Acids | NCT01781559 | Trialant
CompletedInterventionalNot ApplicableUpdated Dec 12, 2013
Bioefficacy of Phenolic Acids
Effect of Phenolic Acids on the Human Vasculature
ClinicalTrials.gov ID
NCT01781559
Lead Sponsor
Société des Produits Nestlé (SPN)INDUSTRY
Overall Status
Completed
Study Type
Interventional
Phase
Not Applicable
Enrollment
14Actual
Last Update Posted
Dec 12, 2013Estimated
Start Date
Oct 2012
Primary Completion Date
Aug 2013Actual
Completion Date
Dec 2013Actual
Official Title
Effect of Phenolic Acids on the Human Vasculature
Brief Summary
The objective is to demonstrate the effect of phenolic acids on endothelial function.
Endothelial Dysfunction
phenolic acid
Ages Eligible for Study
Child (0-17)Adult (18-64)Older Adult (65+)
Sexes Eligible for Study
All
Accepts Healthy Volunteers
Yes
Eligibility Criteria
Inclusion Criteria:
Healthy, Men and women
Subjects with endothelial dysfunction defined as a basal brachial artery flow-mediated dilatation (FMD) measurement between 3% and 8% at screening
Exclusion Criteria:
Any food allergy
Abnormal blood pressure defined as follow: systolic <100 or >160 mmHg and diastolic <50 or >100mmHg
Pregnancy or lactating women
Regular consumption of cholesterol-lowering or antihypertensive medication
Smokers
Inability to restrain from caffeine/tea and alcohol for 12hrs prior to study visits (intake1 day before screening measurements (and 1 day before each visit)
Not restrain the intake of multivitamin-tablets and other supplemental compounds 10 days before the study start and throughout the study.
Excessive alcohol intake defined as > 280 g per week for men and >210g per week for women
Primary Purpose
Supportive Care
Allocation
Randomized
Interventional Model
Crossover Assignment
Masking
Quadruple
No central contacts
There are no central contacts for this study.
School of Medicine and Pharmacology - University of WA