Acute Effect of Polyphenols Supplementation on Endothelial Function and Exercise Related Markers, in Physically Active Healthy Volunteers.

Effets Aigus d'Une supplémentation en polyphénols (Vinitrox™) Contre Placebo Sur la Fonction endothéliale et la Performance Lors d'un Exercice à intensité modérée en Hypoxie Chez Des Volontaires Sains Physiquement Actifs.

To evaluate the effect of acute polyphenols supplementation on vasodilation and related markers along with exercise related markers (notably performance, respiratory exchanges, perceived exertion), before, during and after a hypoxic moderate-intensity exercise in healthy recreative volunteers.

Exercise session is an ergometer cycling workout performed under hypoxia condition equivalent to 3000 meters of altitude. Exercise session is composed of a warmup period followed by 20 minutes of cycling starting at 60% of individual maximal aerobic power.

Inclusion Criteria:

• BMI < 27
• Abdominal circumference < 94 cm
• Stable exercise training program during past 2 months

Exclusion Criteria:

• Total weekly exercise sessions < 4 hours OR > 8 hours
• Drug or supplement intake during past one month that could interfere with study parameters
• Volunteer suffering of respiratory or pulmonary condition
• Volunteer exposed to an altitude > 2000 meters during at least 3 weeks for the past 6 months.