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The investigators performed a 12-week, randomized, double-blind, placebo-controlled human trial to evaluate the efficacy and safety of Fermented Velvet Antler extract on fatigue recovery after exercise. The investigators measured fatigue recovery parameters , including lactate, ammonia, inorganic phosphorus, creatine kinase and LDH, and monitored their blood pressure.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Fermented Velvet Antler extract | Experimental |
| |
| Placebo | Placebo Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Fermented Velvet Antler extract | Dietary Supplement | Fermented Velvet Antler extract (1g/day) |
|
| Measure | Description | Time Frame |
|---|---|---|
| Changes in lactate | Lactate was measured in study visit 1(0 week) and visit 3(12 week). | 12 weeks |
| Changes in ammonia | Ammonia was measured in study visit 1(0 week) and visit 3(12 week). | 12 weeks |
| Changes in inorganic phosphorus | Inorganic phosphorus was measured in study visit 1(0 week) and visit 3(12 week). | 12 weeks |
| Changes in creatine kinase | Creatine kinase was measured in study visit 1(0 week) and visit 3(12 week). | 12 weeks |
| Changes in Lactage dehydrogenase(LDH) | Lactage dehydrogenase(LDH) was measured in study visit 1(0 week) and visit 3(12 week). | 12 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Changes in Multidimensional Fatigue Scale(MFS) | Multidimensional Fatigue Scale(MFS) was measured in study visit 1(0 week) and visit 3(12 week). | 12 weeks |
| Changes in 36-Item Short-Form Health Survey(SF-36) |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Clinical Trial Center for Functional Foods; Chonbuk National University Hospital | Jeonju | Jeollabuk-do | 560-822 | South Korea |
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| ID | Term |
|---|---|
| D015673 | Fatigue Syndrome, Chronic |
| ID | Term |
|---|---|
| D009135 | Muscular Diseases |
| D009140 | Musculoskeletal Diseases |
| D004679 | Encephalomyelitis |
| D000090862 | Neuroinflammatory Diseases |
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| Placebo | Dietary Supplement | Placebo (1g/day) |
|
36-Item Short-Form Health Survey(SF-36) was measured in study visit 1(0 week) and visit 3(12 week).
| 12 weeks |
| D009422 | Nervous System Diseases |
| D009468 | Neuromuscular Diseases |
| D002908 | Chronic Disease |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |