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| Name | Class |
|---|---|
| Inha University Hospital | OTHER |
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The investigators conduct a 8-week, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of ginsengberry concentrate on fatigue.
Previous studies have indicated that ginseng root may have the ability to improve fatigue. Therefore, the investigators conduct a randomized, double-blind, placebo-controlled study to investigate the effects of ginsengberry concentrate on Improvement of Fatigue in adults; the safety of the compound are also evaluate. The Investigators examine FSS(fatigue severity scale), CIS, lactate, Ammonia, Exercise test at baseline, as well as after 4 and 8 weeks of intervention. 88 adults were administered either ginsengberry concentrate or a placebo each day for 8 weeks.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Ginsengberry concentrate | Experimental | This group takes Ginsengberry concentrate for 8 weeks. |
|
| Placebo | Placebo Comparator | This group takes placebo for 8 weeks. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Ginsengberry concentrate | Dietary Supplement | Ginsengberry concentrate |
| |
| Measure | Description | Time Frame |
|---|---|---|
| CIS | Checklist Individual Strength (20-item questionnaire, 1-7 Likert score, the minimum and maximum values is 20~140. Higher scores mean a worse outcome.) | 8 weeks |
| FSS | Fatigue severity Index (9-item questionnaire, 1-7 Likert scale, the minimum and maximum values is 9~63. Higher scores mean a worse outcome.) | 8 weeks |
| NRS | Numeric Rating Scale (for fatigue and Pain. 1-10 point scale. Higher scores mean a worse outcome.) | 8 weeks |
| Blood Indicators Related to Physical Fatigue | lactic acid (mg/dL, Measurement before, immediately after, and after 30 minutes of exercise) | 8 weeks |
| Blood Indicators Related to Mental Fatigue | Cortisol (㎍/dL, Measurement before, immediately after, and after 30 minutes of exercise) | 8 weeks |
| exercise test | VO2max (ml/kg/min, maximal oxygen consumption) | 8 weeks |
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Inclusion Criteria:
- CIS > 76 points
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Kyung Lim Joa, Dr | Inha University Hospital | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Inha University Hospital | Incheon | South Korea |
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| ID | Term |
|---|---|
| D005221 | Fatigue |
| ID | Term |
|---|---|
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| Placebo |
| Dietary Supplement |
Placebo |
|