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| Name | Class |
|---|---|
| BlueProtein | UNKNOWN |
| NutriMar | UNKNOWN |
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The purpose of this study is to compare the possible health benefits of intake of proteins from salmon, herring, cod and milk on glucose tolerance in overweight and obese adults. Overweight and obese subjects often have reduced glucose tolerance, and previous findings from a study on cod proteins suggested that glucose tolerance was improved.
Participants receive 2.5g protein per day for 8 weeks as tablets.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Salmon protein hydrolysate | Experimental |
| |
| Herring protein hydrolysate | Experimental |
| |
| Cod protein | Sham Comparator |
| |
| Milk protein | Placebo Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Salmon protein hydrolysate | Dietary Supplement | 2.5g salmon protein hydrolysate per day for 8wk. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Glucose regulation | Glucose will be measured in fasting and postprandial samples | 8 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Changes in serum insulin, insulin C-peptide, non-esterified fatty acids, lipids, adiponectin, leptin and fatty acid composition | 8 weeks | |
| Changes in serum and urine concentrations of amino acids and their metabolites | 8 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Oddrun A Gudbrandsen, PhD | University of Bergen | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Institute of Medicine, University of Bergen | Bergen | 5021 | Norway |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 30972484 | Derived | Hovland IH, Leikanger IS, Stokkeland O, Waage KH, Mjos SA, Brokstad KA, McCann A, Ueland PM, Slizyte R, Carvajal A, Mellgren G, Remman T, Hogoy I, Gudbrandsen OA. Effects of low doses of fish and milk proteins on glucose regulation and markers of insulin sensitivity in overweight adults: a randomised, double blind study. Eur J Nutr. 2020 Apr;59(3):1013-1029. doi: 10.1007/s00394-019-01963-0. Epub 2019 Apr 10. |
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| ID | Term |
|---|---|
| D009765 | Obesity |
| D050177 | Overweight |
| ID | Term |
|---|---|
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
| D001835 | Body Weight |
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| ID | Term |
|---|---|
| C033061 | Allergen M protein, codfish |
| D008894 | Milk Proteins |
| ID | Term |
|---|---|
| D000080224 | Animal Proteins, Dietary |
| D004044 | Dietary Proteins |
| D011506 | Proteins |
| D000602 | Amino Acids, Peptides, and Proteins |
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| Herring protein hydrolysate | Dietary Supplement | 2.5g herring protein hydrolysate per day for 8wk. |
|
| Cod protein | Dietary Supplement | 2.5g cod protein per day for 8wk. |
|
| Milk protein | Dietary Supplement | 2.5g milk protein per day for 8wk. |
|
| Changes in serum concentrations of vitamins | 8 weeks |
| Comparisons of metabolites and co-factors involved in one-carbon metabolism in serum and urine | Concentrations of relevant metabolites and co-factors were measured in serum and urine | 8 weeks |
| D012816 |
| Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D005502 | Food |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
| D008892 | Milk |
| D003611 | Dairy Products |
| D019602 | Food and Beverages |