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| ID | Type | Description | Link |
|---|---|---|---|
| Callebaut-10151 | Other Identifier | Barry Callebaut Canada Inc |
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As flavanols have antioxidants, anti-inflammatory and anti-DNA damaging effects and may increase microcirculation in skin, the purpose of the study is to investigate the chronic effect of flavanol-rich chocolate as an effective strategy to protect against the harmful effect of ultraviolet (UV) radiation.
Recent data suggested that chronic ingestion of high flavanols cocoa might be a promising agent for dietary photo protection against UV light. Moreover, flavanols-rich cocoa intake has been shown to increase microcirculation in human skin.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Dark chocolate | Experimental | Flavanol-rich chocolate |
|
| Placebo chocolate | Placebo Comparator | Flavanol-free chocolate |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Flavanol-rich chocolate | Other | High-flavanol chocolate, 12 weeks. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in Minimal erythema dose | within the first 12 weeks of chocolate intake and 3 weeks later after end of chocolate consumption |
| Measure | Description | Time Frame |
|---|---|---|
| Change in Skin elasticity | within the first 12 weeks of chocolate intake and 3 weeks later after end of chocolate consumption | |
| Change in Skin moisture | within the first 12 weeks of chocolate intake and 3 weeks later after end of chocolate consumption |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Sylvie Dodin, MD | Laval University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Laval university, Department of Medicine, Institut des nutraceutiques et des aliments fonctionnels. | Québec | Quebec | G1V 0A6 | Canada |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24970388 | Derived | Mogollon JA, Boivin C, Lemieux S, Blanchet C, Claveau J, Dodin S. Chocolate flavanols and skin photoprotection: a parallel, double-blind, randomized clinical trial. Nutr J. 2014 Jun 27;13:66. doi: 10.1186/1475-2891-13-66. |
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| Flavanol-free chocolate | Other | Flavanol-free chocolate, 12 weeks |
|
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| Change in levels of Vitamin D and polyphenols | within the first 12 weeks of chocolate intake and 3 weeks later after end of chocolate consumption |