Comparison for Pethidine Requirement in Patients Received Spinal Morphine 0.2 and 0.3 mg for Post Lobectomy Analgesia

Comparison for Pethidine Requirement in Patients Received Spinal Morphine 0.2 and 0.3 Milligram for Post Lobectomy (Lung) Analgesia

The purpose of the study is to evaluate the amount of total pethidine requirement during the 48 hour postoperative period after receiving spinal morphine 0.2 and 0.3 mg.

Thoracotomy causes severe pain to the patients. Continuous thoracic epidural is a gold standard for postoperative pain. However, it needs skill. There are many alternatives such as spinal morphine, intercostal nerve block, cryoalangesia or interpleural block.

Inclusion Criteria:

• Age > 18 year and < 70 year
• Patient ASA physical status I-III.
• Scheduled for thoracotomy with lobectomy.
• Can operate a patient-controlled analgesia (PCA) device.

Exclusion Criteria:

• Known hypersensitivity to morphine or pethidine
• History of bleeding tendency.
• Known case of infection at the back
• Patient refuse for spinal anesthesia
• History of cerebrovascular disease.
• Scheduled for video-assisted thoracoscopic lobectomy.
• Need mechanical ventilatory support during postoperative period