Comparison of Hyperemic Efficacy Between Central and Peripheral Adenosine Infusion for Fractional Flow Reserve (FFR) Measurement

The purpose of this study is to evaluate the safety and effectiveness of the peripheral IV continuous infusion without the insertion of central venous vascular access method in the achievement of steady-state maximal coronary hyperemia compared with the central IV continuous infusion method.

Inclusion Criteria:

• non -infarct related, patients with moderate coronary artery stenosis
• normal ejection fraction on echocardiogram

Exclusion Criteria:

• infarct-related arteries or clinically unstable state
• collateral blood flow to the target vessel is shown
• atrioventricular block on electrocardiogram
• reduced ejection fraction(<50%) or left ventricular hypertrophy on echocardiography
• contraindication of adenosine