Comparison of Hyperemic Efficacy Between Nicorandil and Adenosine for Fractional Flow Reserve (FFR) Measurement

The purpose of this study is to evaluate the efficacy of nicorandil in the achievement of maximal coronary hyperemia compared with adenosine.

Inclusion Criteria:

• non -infarct related, patients with moderate coronary artery stenosis
• normal left ventricular ejection fraction on echocardiogram

Exclusion Criteria:

• infarct-related arteries or clinically unstable state
• collateral blood flow to the target vessel is shown
• atrioventricular block on electrocardiogram
• reduced left ventricular ejection fraction (<50%) or left ventricular hypertrophy on echocardiogram
• contraindication of adenosine
• bronchial asthma