308 nm excimer lamp and 308 nm excimer laser have both provide interesting results in treating vitiligo. They have the same wavelength but the type of emission of the photons is different. To date there is no direct comparative data concerning these two devices in this indication.

The aim of the study is to make an intra-individual prospective comparison between these two phototherapies.

Inclusion Criteria:

• patient above 18
• vitiligo for more than 3 months
• at least 2 vitiligo symmetric patches more than 10cm²
• to read and understand the inform consent
• to have a social security number
• non pregnant for women

Exclusion Criteria:

• pregnant women
• keloids
• history of radiotherapy or skin cancer in the treated areas
• treatment for vitiligo in the past 4 weeks
• phototherapy in the past 12 weeks; history of photodermatosis
• treatment inducing photosensibilization
• immunosuppression
• patient who participated in a study in the past 3 months